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KMID : 1035520130010010045
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Brain Tumor Research and Treatment : BTRT
2013 Volume.1 No. 1 p.45 ~ p.49
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5-Aminolevulinic Acid Fluorescence Discriminates the Histological Grade of Extraventricular Neurocytoma
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Song Sang-Woo
Kim Young-Hoon
Park Sung-Hye
Park Chul-Kee
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Abstract
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Extraventricular neurocytomas are rare brain tumors that have a diverse range of clinical characteristics. We describe two cases involving fluorescence-guided resection of extraventricular neurocytoma using 5-aminolevulinic acid (5-ALA) and evaluate the efficacy of the technique. We found that the tumor reactions to 5-ALA differed depending on the histologic grade. This finding shows that the 5-ALA fluorescence reaction may potentially be used as a biomarker of the clinical behavior of these tumors. To our knowledge, this is the first report in which fluorescence-guided resection was utilized for the resection of extraventricular neurocytomas.
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KEYWORD
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Extraventricular neurocytoma, Fluorescence guided surgery, 5-aminolevulinic acid
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